SCHEMBL1065689

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL24445857	0.87	MRGPRX4 (0.40)	TUBB1RETKIF5BKDRLMNA
	SCHEMBL14882573	0.86	MAPT (0.50)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL4302346	0.82	MAPK1 (0.46)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL27494626	0.80	TUBB1 (0.41)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL31644868	0.78	ERN1 (0.50)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL23723768	0.78	ALDH1A1 (0.41)	TUBB1RETKIF5BKDRLMNA
	SCHEMBL2549340	0.78	IDO1 (0.44)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL23723833	0.78	KMT2A (0.42)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL25937354	0.78	ERN1 (0.42)	TUBB1LMNAMAPK1TP53MAPT
	SCHEMBL31143077	0.78	LMNA (0.39)	TUBB1LMNAMAPK1TP53MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.