Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.33 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.33 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.33 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.33 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.33 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.33 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.33 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.33 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10733392 | 0.80 | FFAR4 (0.39) | PTGS1KDM4EGPBAR1ANO1FFAR4 | |
| SCHEMBL10662256 | 0.79 | ALDH1A1 (0.44) | PTGS1ALDH1A1KDM4EGPBAR1FFAR4 | |
| SCHEMBL10655745 | 0.79 | NPC1 (0.43) | PTGS1ALDH1A1KDM4ETUBB4ATUBB | |
| SCHEMBL10730831 | 0.79 | FFAR4 (0.39) | PTGS1GPBAR1ANO1FFAR4NPC1 | |
| Hydrochloric Acid SCHEMBL10729202 | 0.79 | TP53 (0.39) | PTGS1KDM4EGPBAR1ANO1FFAR4 | |
| SCHEMBL10661817 | 0.79 | FFAR4 (0.41) | PTGS1GPBAR1FFAR4NPC1PPARA | |
| SCHEMBL10662964 | 0.78 | TSHR (0.43) | PTGS1ALDH1A1KDM4EGPBAR1FFAR4 | |
| SCHEMBL10658060 | 0.78 | ALDH1A1 (0.42) | PTGS1ALDH1A1KDM4EGPBAR1FFAR4 | |
| SCHEMBL10736238 | 0.78 | SLC6A9 (0.39) | PTGS1GPBAR1FFAR4PPARAPPARG | |
| SCHEMBL10660661 | 0.78 | CTSS (0.41) | PTGS1GPBAR1ANO1FFAR4GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4728662-A | DIURETICS, URICOSURICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) | 1988-03-01 | — | — | US | disclosed |
| US-4673746-A | DIURETICS, HYPOTENSIVES | HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) | 1987-06-16 | — | — | US | disclosed |
| EP-0002666-A1 | 1,2-Benzisoxazolyloxy (or thio) acetic acids and related compounds, process for their preparation and medicines containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-07-11 | — | — | EP | disclosed |