Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | PPARA | Q07869 | 2/20 | 0.40 |
| ▸ | GMNN | O75496 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL2135218 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Glycinebetaine SCHEMBL2133338 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Glycinebetaine SCHEMBL2132643 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Glycinebetaine SCHEMBL2131138 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Glycinebetaine SCHEMBL3889766 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Glycinebetaine SCHEMBL1065800 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Glycinebetaine SCHEMBL156318 | 0.92 | GPR84 (0.41) | FFAR1MAPTPPARDNPSR1 | |
| Oleic Acid SCHEMBL2161441 | 0.88 | PPARG (0.47) | FABP3SLC6A5FFAR1FFAR4TERT | |
| SCHEMBL25406807 | 0.87 | TERT (0.51) | FFAR1FFAR4TERTPTPN1MAPT | |
| SCHEMBL15155723 | 0.87 | TERT (0.51) | FFAR1FFAR4TERTPTPN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9119991-B2 | Golf ball resin composition and golf ball | DUNLOP SPORTS CO. LTD. (JP) | 2015-09-01 | — | — | US | claimed |
| US-10661124-B2 | Golf ball resin composition and golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2020-05-26 | — | — | US | disclosed |
| US-10195489-B2 | Golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2019-02-05 | — | — | US | disclosed |
| US-20180353814-A1 | GOLF BALL RESIN COMPOSITION AND GOLF BALL | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-12-13 | — | — | US | disclosed |
| US-10099089-B2 | Golf ball resin composition and golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-10-16 | — | — | US | disclosed |
| US-10080924-B2 | Golf ball | SUMITOMO RUBBER INDUSTRIES, LTD. (JP) | 2018-09-25 | — | — | US | disclosed |
| EP-2668978-B1 | Golf ball | DUNLOP SPORTS CO LTD (JP) | 2017-09-13 | — | — | EP | disclosed |
| US-20170136309-A1 | GOLF BALL RESIN COMPOSITION AND GOLF BALL | DUNLOP SPORTS CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| EP-2668979-B1 | Golf ball | DUNLOP SPORTS CO LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-20150375051-A1 | GOLF BALL RESIN COMPOSITION AND GOLF BALL | DUNLOP SPORTS CO., LTD. (JP) | 2015-12-31 | — | — | US | disclosed |
| US-20130172112-A1 | GOLF BALL RESIN COMPOSITION AND GOLF BALL | DUNLOP SPORTS CO. LTD. (JP) | 2013-07-04 | — | — | US | disclosed |
| US-8288329-B2 | Hair-treatment composition and hair-treatment method using same | HOYU CO., LTD (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120207689-A1 | COSMETIC PREPARATION FOR HAIR AND METHOD FOR APPLICATION THEREOF | HOYU CO., LTD. (JP) | 2012-08-16 | — | — | US | disclosed |
| US-20120100091-A1 | HAIR-TREATMENT COMPOSITION AND HAIR-TREATMENT METHOD USING SAME | HOYU CO., LTD. (JP) | 2012-04-26 | — | — | US | disclosed |
| EP-1163895-B1 | DETERGENT COMPOSITIONS | KAO CORP (JP) | 2008-08-13 | — | — | EP | disclosed |
| US-6509304-B1 | Comprising anionic surfactants, amphoteric surfactants or hydrophilic nonionic surfactants; fibers; and a liquid oil for cleansing skin and removing make-up | KAO CORPORATION (JP) | 2003-01-21 | — | — | US | disclosed |
| EP-1163895-A1 | DETERGENT COMPOSITIONS | Kao Corporation (JP) | 2001-12-19 | — | — | EP | disclosed |
| EP-0356784-B1 | Liquid detergent composition | MITSUBISHI PETROCHEMICAL CO (JP) | 1993-11-10 | — | — | EP | disclosed |
| US-5000877-A | Aqueous liquid detergent containing an N-acylaspartate and a betaine or imidazoline surfactant | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1991-03-19 | — | — | US | disclosed |
| EP-0356784-A2 | Liquid detergent composition | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100091-A1 | HAIR-TREATMENT COMPOSITION AND HAIR-TREATMENT METHOD USING SAME | AADAT, BHMT2, BCAT2 | FABP3 1034/4885SLC6A5 1189/4885FFAR1 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.