Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.38 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CPT2 | P23786 | 1/20 | 0.33 |
| ▸ | CPT1A | P50416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL2135218 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL156318 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL2133338 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL3889766 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL2131138 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL1065800 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL2132643 | 0.88 | GPR84 (0.41) | ACE2GRIK1GRIK2GPR84CA1 | |
| Glycinebetaine SCHEMBL2131980 | 0.81 | FABP3 (0.46) | FFAR1MAPTPPARDCYP2C9CYP2C19 | |
| Glycinebetaine SCHEMBL3879924 | 0.81 | CA2 (0.44) | GRIK1GRIK2SLC1A2SLC1A1CA2 | |
| Glycinebetaine SCHEMBL1893593 | 0.79 | CHRM1 (0.39) | GRIK1GRIK2SLC1A2SLC1A1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8216559-B2 | Deodorant fiber and fibrous article and product made thereof | JNC CORPORATION (JP) | 2012-07-10 | — | — | US | disclosed |
| US-20050255078-A1 | Deodorant fiber and fibrous article and product made thereof | CHISSO CORPOARTION (JP) | 2005-11-17 | — | — | US | disclosed |