Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Glycinebetaine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycinebetaine SCHEMBL2131138 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| Glycinebetaine SCHEMBL156318 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| Glycinebetaine SCHEMBL3889766 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| Glycinebetaine SCHEMBL2132643 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| Glycinebetaine SCHEMBL1065800 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| Glycinebetaine SCHEMBL2135218 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| Glycinebetaine SCHEMBL2133338 | 0.88 | GPR84 (0.41) | TSHRNFKB1NPSR1GRIK1SLC1A2 | |
| SCHEMBL3108862 | 0.87 | GRIK1 (0.38) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Octadecanoic Acid Amide SCHEMBL2065217 | 0.87 | TP53 (0.37) | TSHRCYP3A4NFKB1GRIK1GRIK2 | |
| Palmitamide SCHEMBL2065209 | 0.87 | TP53 (0.37) | TSHRCYP3A4NFKB1GRIK1GRIK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3632998-B1 | INK, PRINTED ARTICLE, AND METHOD OF MANUFACTURING PRINTED ARTICLE | DAINIPPON INK & CHEMICALS (JP) | 2023-12-13 | — | — | EP | disclosed |
| US-20220213309-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME | DOW TORAY CO., LTD. (JP) | 2022-07-07 | — | — | US | disclosed |
| EP-3950727-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME | Dow Toray Co., Ltd. (JP) | 2022-02-09 | — | — | EP | disclosed |
| US-11180595-B2 | Copolymer having carbosiloxane dendrimer structure and acidic group, composition containing same, and cosmetic | DOW TORAY CO., LTD. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-10874604-B2 | Cosmetic composition or external composition, and cosmetic raw material composition | DOW TORAY CO., LTD. (JP) | 2020-12-29 | — | — | US | disclosed |
| US-20200247928-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE AND ACIDIC GROUP, COMPOSITION CONTAINING SAME, AND COSMETIC | DOW TORAY CO., LTD. (JP) | 2020-08-06 | — | — | US | disclosed |
| US-20200038312-A1 | COSMETIC COMPOSITION OR EXTERNAL COMPOSITION, AND COSMETIC RAW MATERIAL COMPOSITION | DOW TORAY CO., LTD. (JP) | 2020-02-06 | — | — | US | disclosed |
| EP-3524228-A1 | COSMETIC COMPOSITION OR EXTERNAL COMPOSITION, AND COSMETIC RAW MATERIAL COMPOSITION | Dow Silicones Corporation (US) | 2019-08-14 | — | — | EP | disclosed |
| EP-2310060-B1 | COATING METHOD FOR MEDICAL DEVICES | FUJIFILM MFG EUROPE BV (NL) | 2013-02-27 | — | — | EP | disclosed |
| WO-2013018356-A1 | METHOD FOR PRODUCING COMPOSITE PARTICLE, METHOD FOR PRODUCING COSMETIC, AND COSMETIC | SHIN-ETSU CHEMICAL CO.,LTD. (JP) | 2013-02-07 | — | — | WO | disclosed |
| EP-1080934-B1 | Ink-jet printing receiving sheet comprising gelatin and a metal salt | FERRANIA SPA (IT) | 2003-10-29 | — | — | EP | disclosed |
| US-6592953-B1 | Receiving sheet for ink-jet printing comprising a copolymer | FERRANIA, S.P.A. (IT) | 2003-07-15 | — | — | US | disclosed |
| EP-1080937-B1 | Ink-receiving sheet for ink-jet printing comprising a mixture of gelatin and saccharides | FERRANIA SPA (IT) | 2003-03-12 | — | — | EP | disclosed |
| US-6387473-B1 | Receiving sheet for ink-jet printing comprising a surfactant combination | FERRANIA S.P.A. (IT) | 2002-05-14 | — | — | US | disclosed |
| EP-1101625-A2 | Receiving sheet for ink-jet printing comprising a copolymer | FERRANIA S.p.A. (IT) | 2001-05-23 | — | — | EP | disclosed |
| EP-1080934-A1 | Ink-jet printing receiving sheet comprising gelatin and a metal salt | FERRANIA S.p.A. (IT) | 2001-03-07 | — | — | EP | disclosed |
| EP-1080935-A2 | Ink-jet print receiving sheet comprising a high-boiling organic solvent and an non-ionic surfactant | FERRANIA S.p.A. (IT) | 2001-03-07 | — | — | EP | disclosed |
| EP-1080937-A1 | Ink-receiving sheet for ink-jet printing comprising a mixture of gelatin and saccharides | FERRANIA S.p.A. (IT) | 2001-03-07 | — | — | EP | disclosed |
| EP-1080936-A2 | Receiving sheet for ink-jet printing comprising a surfactant combination | FERRANIA S.p.A. (IT) | 2001-03-07 | — | — | EP | disclosed |
| EP-0356784-A2 | Liquid detergent composition | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1990-03-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200247928-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE AND ACIDIC GROUP, COMPOSITION CONTAINING SAME, AND COSMETIC | WASHC5, ADCY1, ADCY8 | CHRM1 157/4885AKR1A1 778/4885CHRM3 813/4885 |
| US-10874604-B2 | Cosmetic composition or external composition, and cosmetic raw material composition | H1-0, CUTA, HAO2 | CHRM1 491/4885AKR1A1 2928/4885CHRM3 1320/4885 |
| US-11180595-B2 | Copolymer having carbosiloxane dendrimer structure and acidic group, composition containing same, and cosmetic | WASHC5, ADCY1, ADCY8 | CHRM1 157/4885AKR1A1 778/4885CHRM3 813/4885 |
| US-20200038312-A1 | COSMETIC COMPOSITION OR EXTERNAL COMPOSITION, AND COSMETIC RAW MATERIAL COMPOSITION | H1-0, CUTA, HAO2 | CHRM1 491/4885AKR1A1 2928/4885CHRM3 1320/4885 |
| US-20220213309-A1 | COPOLYMER HAVING CARBOSILOXANE DENDRIMER STRUCTURE, AND COMPOSITION, COSMETIC INGREDIENT, COATING FORMING AGENT, AND COSMETIC CONTAINING SAME | ADCY1, ADORA1, ADCY8 | CHRM1 8/4885AKR1A1 411/4885CHRM3 335/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.