Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.46 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 9/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.36 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.35 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.35 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.35 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10658721 | 1.00 | PDE3B (0.46) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10657585 | 0.83 | PTPN1 (0.46) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10657595 | 0.83 | PTPN1 (0.46) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10656359 | 0.80 | PTPN1 (0.45) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10656364 | 0.80 | PTPN1 (0.45) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10659724 | 0.80 | PDE3B (0.46) | PDE3BPDE3AP2RY12MAPTHTT | |
| SCHEMBL10657645 | 0.78 | PDE3B (0.42) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10657656 | 0.78 | PDE3B (0.42) | PDE3BPDE3AP2RY12HPGDMAPT | |
| SCHEMBL10754644 | 0.77 | ALDH1A1 (0.47) | HPGDMAPTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL10754642 | 0.77 | ALDH1A1 (0.47) | HPGDMAPTSMN1; SMN2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4775674-A | CARDIOTONIC AGENTS | BRISTOL-MYERS COMPANY (US) | 1988-10-04 | — | — | US | disclosed |