Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.53 |
| ▸ | RAB9A | P51151 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.53 |
| ▸ | RELA | Q04206 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9490199 | 0.87 | ALDH1A1 (0.51) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9869826 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9679476 | 0.86 | ALDH1A1 (0.50) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9770307 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9770312 | 0.82 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL8744442 | 0.81 | PRSS1 (0.48) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6633145 | 0.72 | KDM4E (0.55) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL9831920 | 0.72 | ALDH1A1 (0.54) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL8573566 | 0.71 | RAB9A (0.50) | ALDH1A1KDM4ENPC1RAB9AMAPT | |
| SCHEMBL7820902 | 0.71 | RAB9A (0.50) | ALDH1A1KDM4ENPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739054-A | FOR METALS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-04-19 | — | — | US | disclosed |
| US-4675172-A | COPPER, CADMIUM, COBALT, ZINC | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-06-23 | — | — | US | disclosed |