Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.54 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6632656 | 0.77 | ADORA3 (0.50) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL6633419 | 0.74 | CSNK1D (0.73) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL22932832 | 0.74 | KDM4E (0.51) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL30781549 | 0.74 | ADORA3 (0.49) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL6631279 | 0.73 | ADORA3 (0.62) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL31682544 | 0.73 | NPC1 (0.49) | KDM4ENPC1RAB9ACSNK1DALDH1A1 | |
| SCHEMBL6633978 | 0.73 | CSNK1D (0.72) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL10658769 | 0.72 | ALDH1A1 (0.54) | KDM4ENPC1RAB9ACSNK1DALDH1A1 | |
| SCHEMBL6632337 | 0.72 | SMN1; SMN2 (0.50) | KDM4ENPC1RAB9AADORA3ADORA2A | |
| SCHEMBL9490199 | 0.71 | ALDH1A1 (0.51) | KDM4ENPC1RAB9ACSNK1DALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1430898-A1 | RECEPTOR ANTAGONIST | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-23 | — | — | EP | disclosed |
| US-20040110826-A1 | Receptor Antagonists | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110826-A1 | Receptor Antagonists | ADRA2C, OPRL1, ADRB1 | KDM4E 2973/4885NPC1 3041/4885RAB9A 314/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.