Known targets — ChEMBL curated mechanism
ACEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ATP4AATP4BAXLBTKCACNA1CCACNA1DCACNA1FCACNA1SCCR5CHRM2CHRM3CPT1BCPT2DPP4DRD1DRD2EGFRERBB2ERBB4FLT3HRH1HRH3HTR1AHTR2AHTR2BHTR2CHTR4JAK1JAK2JAK3KCNH2KMT2AMAP2K1MAP2K2MEN1MLNRMPLMTORPPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PLK4PPARGRENS1PR1SLC6A2SLC6A3SLC6A4SMOTYK2atpAatpBatpCatpDatpEatpFatpFHatpGpol
The experimentally established mechanism targets of Fumaric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL28608401 | 1.00 | TSHR (0.60) | — | |
| Maleic Acid SCHEMBL11157243 | 1.00 | TSHR (0.60) | — | |
| Fumaric Acid SCHEMBL30578900 | 1.00 | TSHR (0.60) | — | |
| Fumaric Acid SCHEMBL106606 | 1.00 | — | — | |
| Maleic Acid SCHEMBL8163405 | 1.00 | TSHR (0.60) | — | |
| Fumaric Acid SCHEMBL107031 | 1.00 | — | — | |
| Fumaric Acid SCHEMBL263297 | 1.00 | TSHR (0.60) | — | |
| Maleic Acid SCHEMBL7961962 | 1.00 | TSHR (0.60) | — | |
| Fumaric Acid SCHEMBL263298 | 1.00 | TSHR (0.60) | — | |
| Fumaric Acid SCHEMBL5799074 | 1.00 | TSHR (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1673 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4682143-A1 | PHARMACEUTICAL COMPOSITION CONTAINING EGFR INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Convalife Pharmaceuticals Co., Ltd. (CN) | 2026-01-21 | — | — | EP | claimed |
| EP-4659850-A2 | IMPROVED PROTEIN RECOVERY | Bristol-Myers Squibb Company (US) | 2025-12-10 | — | — | EP | claimed |
| EP-3837273-B1 | IMPROVED PROTEIN RECOVERY | BRISTOL MYERS SQUIBB CO (US) | 2025-09-24 | — | — | EP | claimed |
| CN-120192358-A | Organic acid salt and crystal form of nicotinamide riboside and preparation method of organic acid salt and crystal form | 上海昱菘生物科技有限公司 | 2025-06-24 | — | — | CN | claimed |
| WO-2025097045-A1 | COLLOIDAL FOOD BASE COMPOSITIONS COMPRISING MYCELIAL BIOMASS | THE FYNDER GROUP, INC (US) | 2025-05-08 | — | — | WO | claimed |
| CN-119867276-A | Live bacteria soup ladle, preparation method and application thereof | 广州弘海材料科技有限公司 | 2025-04-25 | — | — | CN | claimed |
| US-20250127776-A1 | ORAL PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2025-04-24 | — | — | US | claimed |
| US-20250092090-A1 | PROTEIN RECOVERY | BRISTOL-MYERS SQUIBB COMPANY (US) | 2025-03-20 | — | — | US | claimed |
| CN-119101400-A | Edible consumable, preparation method thereof and food surface printing process | 武汉膳印科技有限公司 | 2024-12-10 | — | — | CN | claimed |
| CN-119073530-A | Smearing liquid and smearing method for regulating sausage casing performance of sausage products | 河南工业大学 | 2024-12-06 | — | — | CN | claimed |
| US-5208153-A | Culturing Streptomyces spectabilis | SHIN-ETSU BIO, INC. (US) | 1993-05-04 | — | — | US | claimed |
| EP-0538050-A2 | Process for producing streptovaricin C | SHIN-ETSU BIO, Inc. (US) | 1993-04-21 | — | — | EP | claimed |
| US-5126254-A | Culturing Streptomyces in presence of nonionic adsorbent | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1992-06-30 | — | — | US | claimed |
| US-5114846-A | Culture of streptomyces and selecting the asprogenous colonies | SHIN-ETSU BIO, INC. (US) | 1992-05-19 | — | — | US | claimed |
| CN-1039522-A | The expellent of algae and bacterium class | NIPPON CATALYTIC CHEM IND (JP) | 1990-02-14 | — | — | CN | claimed |
| US-4472447-A | 5'-NUCLEOTIDE, ALKALI SALT OF ORGANIC ACID | AJINOMOTO CO., INC. (JP) | 1984-09-18 | — | — | US | claimed |
| EP-0031162-B1 | MIXED SEASONING ON BASIS OF MONOSODIUM L-GLUTAMATE | AJINOMOTO CO., INC. (JP) | 1983-10-12 | — | — | EP | claimed |
| EP-0031162-A1 | Mixed seasoning on basis of monosodium L-glutamate | AJINOMOTO CO., INC. (JP) | 1981-07-01 | — | — | EP | claimed |
| US-4258072-A | MSG, A 5'-NUCLEOTIDE, SUCCINIC ACID OR SODIUM SUCCINATE, SALT OF AN ORGANIC ACID | AJINOMOTO CO., INC. (JP) | 1981-03-24 | — | — | US | claimed |
| US-4053612-A | FUNGICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-10-11 | — | — | US | claimed |