Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 4/20 | 0.40 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.40 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 7/20 | 0.37 |
| ▸ | KLK7 | P49862 | 1/20 | 0.36 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10668227 | 0.86 | CTSK (0.49) | CTSKCTSSUSP30ACEITGB3 | |
| SCHEMBL10663870 | 0.85 | ITGB3 (0.41) | CTSKCTSSITGB3ITGA2BSIRT5 | |
| SCHEMBL11393750 | 0.85 | CTSK (0.41) | CTSKCTSSUSP30ACEITGB3 | |
| SCHEMBL11075153 | 0.84 | ACE (0.38) | ACEITGB3ITGA2BSIRT5CXCR3 | |
| SCHEMBL10668564 | 0.75 | KMT2A (0.59) | ACEITGB3ITGA2B | |
| SCHEMBL10668348 | 0.72 | ACE (0.48) | CTSKCTSSACE | |
| SCHEMBL16847748 | 0.70 | CTSS (0.54) | CTSKCTSSITGB3KLK7KLK5 | |
| SCHEMBL11040565 | 0.70 | CTSB (0.47) | CTSKCTSSACE | |
| SCHEMBL19982985 | 0.70 | MEN1 (0.52) | ACEITGB3ITGA2B | |
| SCHEMBL19665743 | 0.70 | MEN1 (0.52) | ACEITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0036713-B1 | ANGIOTENSIN CONVERTING ENZYME INHIBITORS | UNIVERSITY OF MIAMI (US) | 1984-01-18 | — | — | EP | disclosed |