Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 4/20 | 0.56 |
| ▸ | CA2 | P00918 | 4/20 | 0.56 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA6 | P23280 | 3/20 | 0.56 |
| ▸ | CA7 | P43166 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.56 |
| ▸ | CA4 | P22748 | 2/20 | 0.56 |
| ▸ | CA3 | P07451 | 2/20 | 0.56 |
| ▸ | TYR | P14679 | 2/20 | 0.56 |
| ▸ | CA5A | P35218 | 2/20 | 0.56 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL2511919 | 0.78 | TSHR (1.00) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL175823 | 0.78 | TSHR (1.00) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL5053781 | 0.78 | TSHR (1.00) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL1655 | 0.78 | TSHR (1.00) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL27943509 | 0.75 | CA12 (0.95) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL25381766 | 0.74 | TSHR (0.92) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL996091 | 0.74 | TSHR (0.92) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL9484769 | 0.74 | TSHR (0.92) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL21443891 | 0.74 | TSHR (0.92) | TSHRTP53CA1CA2CA12 | |
| Terephthalic Acid SCHEMBL20704876 | 0.74 | TSHR (0.92) | TSHRTP53CA1CA2CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4754041-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1988-06-28 | — | — | US | disclosed |
| US-4638062-A | 3-acylamino-2-oxo-1-azetidinesulfonic acids | E. R. SQUIBB & SONS, INC. (US) | 1987-01-20 | — | — | US | disclosed |