Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | GALR3 | O60755 | 1/20 | 0.30 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.30 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.30 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10671463 | 0.90 | ALDH1A1 (0.36) | LMNAHIF1A | |
| SCHEMBL10670260 | 0.75 | LMNA (0.47) | LMNA | |
| SCHEMBL10667105 | 0.73 | HIF1A (0.38) | ADRB2LMNAHIF1ASLC6A2SLC6A4 | |
| SCHEMBL10670001 | 0.71 | HIF1A (0.47) | ADRB2LMNAHIF1ACYP2D6GALR3 | |
| SCHEMBL10663277 | 0.70 | LMNA (0.48) | LMNA | |
| SCHEMBL10671458 | 0.70 | CYP2D6 (0.43) | ADRB2CYP2D6ADRB3 | |
| SCHEMBL10569784 | 0.64 | MEN1 (0.46) | ADRB2LMNAOPRM1CYP2D6ADRB1 | |
| SCHEMBL10669676 | 0.62 | ADRB1 (0.51) | ADRB2LMNAHIF1AGALR3ADRB1 | |
| SCHEMBL9811836 | 0.61 | TDP1 (0.44) | ADRB2LMNAHIF1ASLC6A2SLC6A4 | |
| SCHEMBL10668073 | 0.57 | MMP2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4721717-A | α-(aminoalkylaminomethyl)phenylmethanols, composition containing them, and use thereof to treat certain heart and circulatory diseases | BOEHRINGER MANNHEIM GMBH (DE) | 1988-01-26 | — | — | US | disclosed |