Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SLC1A5 | Q15758 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9999395 | 0.93 | TSHR (0.53) | HRH1SLC6A4SLC6A2RIPK1TSHR | |
| SCHEMBL1067253 | 0.83 | HRH1 (0.67) | HRH1SLC6A4SLC6A2RIPK1TSHR | |
| SCHEMBL2061855 | 0.80 | HRH1 (0.51) | HRH1SLC6A4SLC6A2RIPK1FFAR1 | |
| SCHEMBL1070099 | 0.80 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1FFAR1 | |
| SCHEMBL8516631 | 0.77 | HRH1 (0.59) | HRH1SLC6A4SLC6A2RIPK1FFAR1 | |
| SCHEMBL2062575 | 0.77 | LTA4H (0.56) | TSHRHSD17B10FFAR1MMP2MMP9 | |
| SCHEMBL16111413 | 0.75 | HRH1 (0.67) | HRH1SLC6A4SLC6A2RIPK1TSHR | |
| SCHEMBL2061852 | 0.75 | HRH1 (0.53) | HRH1SLC6A4SLC6A2RIPK1FFAR1 | |
| SCHEMBL194417 | 0.75 | HRH1 (0.60) | HRH1SLC6A4SLC6A2RIPK1TSHR | |
| SCHEMBL6503487 | 0.73 | HRH1 (0.62) | HRH1SLC6A4SLC6A2RIPK1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2888224-B1 | PHENOXY ALKYL DIETHANOLAMINE AND DIISOPROPANOLAMINE COMPOUNDS FOR DELIVERING ACTIVE AGENTS | EMISPHERE TECH INC (US) | 2017-11-15 | — | — | EP | disclosed |
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8148578-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2012-04-03 | — | — | US | disclosed |
| US-8076333-B2 | Fast acting naratriptan composition | EMISPHERE TECHNOLOGIES INC. (US) | 2011-12-13 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES, INC. (US) | 2011-12-08 | — | — | US | disclosed |
| US-20090253702-A1 | FAST ACTING NARATRIPTAN COMPOSITION | EMISPHERE TECHNOLOGIES INC. (US) | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253702-A1 | FAST ACTING NARATRIPTAN COMPOSITION | HTR1D, HTR3E, HPD | HRH1 212/4885SLC6A4 24/4885SLC6A2 115/4885 |
| US-20110301244-A1 | FAST ACTING NARATRIPTAN COMPOSITION | HTR1D, HTR3E, HPD | HRH1 212/4885SLC6A4 24/4885SLC6A2 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.