Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.53 |
| ▸ | RARG | P13631 | 9/20 | 0.53 |
| ▸ | RARA | P10276 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.53 |
| ▸ | GOT1 | P17174 | 1/20 | 0.53 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9300831 | 0.82 | RARB (0.69) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL8458032 | 0.81 | RARG (0.74) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9622135 | 0.77 | RARB (0.61) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL7052829 | 0.75 | RARG (0.70) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9622121 | 0.73 | ALDH1A1 (0.53) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6535667 | 0.73 | RARG (0.74) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL6878528 | 0.72 | KMT2A (0.51) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL11826391 | 0.72 | NR4A2 (0.58) | TDP1KDM4ETP53MAPTALDH1A1 | |
| SCHEMBL29222875 | 0.71 | WDR5 (0.45) | RARBRARGRARAMEN1KMT2A | |
| SCHEMBL9622379 | 0.70 | RARB (0.50) | RARBRARGRARAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4740519-A | Benzo (b) thiophene carboxylate derivatives and pharmaceutical compositions | CENTRE INTERNATIONAL DE RECHERCHES DERMATOLOGIQUES C.I.R.D. (FR) | 1988-04-26 | — | — | US | disclosed |