Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068136 | 0.88 | CYP1A2 (0.49) | CYP2C19CYP2C9MMP2MEN1KMT2A | |
| SCHEMBL12933711 | 0.87 | ABCB1 (0.43) | CYP3A4CYP2C19CYP2C9ALDH1A1MMP2 | |
| SCHEMBL12933684 | 0.83 | CYP3A4 (0.49) | CYP3A4CYP2C19CYP2C9ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL2787536 | 0.82 | CYP3A4 (0.48) | CYP3A4CYP2C19CYP2C9ALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL2787531 | 0.82 | CYP3A4 (0.48) | CYP3A4CYP2C19CYP2C9ALDH1A1MEN1 | |
| SCHEMBL12933712 | 0.76 | ALDH1A1 (0.49) | CYP2C19CYP2C9ALDH1A1MMP2MEN1 | |
| SCHEMBL1066478 | 0.74 | MAPK1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL12933704 | 0.74 | MAPK1 (0.46) | ALDH1A1KMT2A | |
| SCHEMBL5470679 | 0.73 | CA12 (0.46) | ALDH1A1MMP2L3MBTL1 | |
| SCHEMBL12933681 | 0.70 | CYP1A2 (0.55) | CYP2C19CYP2C9SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868206-B2 | Trihalomethionine derivative and pharmaceutical product containing the same | National University Corporation, Gunma University (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100076224-A1 | NOVEL TRIHALOMETHIONINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING THE SAME | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076224-A1 | NOVEL TRIHALOMETHIONINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING THE SAME | CTH, MTR, BHMT | CYP3A4 262/4885CYP2C19 472/4885CYP2C9 367/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.