Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MMP2 | P08253 | 4/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1067702 | 0.88 | CYP3A4 (0.44) | CYP2C9CYP2C19TSHRKMT2AMMP2 | |
| SCHEMBL12933712 | 0.88 | ALDH1A1 (0.49) | CYP1A2CYP2C9CYP2C19LMNATSHR | |
| SCHEMBL12933681 | 0.83 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2787934 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19LMNASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL2787939 | 0.82 | CYP1A2 (0.54) | CYP1A2CYP2C9CYP2C19LMNASMN1; SMN2 | |
| SCHEMBL2788208 | 0.80 | HDAC1 (0.40) | SMN1; SMN2MAPT | |
| SCHEMBL12933711 | 0.76 | ABCB1 (0.43) | CYP2C9CYP2C19LMNAKMT2AMMP2 | |
| SCHEMBL5457763 | 0.74 | HDAC6 (0.47) | LMNATSHRKMT2AMMP2FPR2 | |
| SCHEMBL12933699 | 0.71 | HDAC4 (0.55) | — | |
| SCHEMBL1066478 | 0.71 | MAPK1 (0.46) | LMNAKMT2AHPGDMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7868206-B2 | Trihalomethionine derivative and pharmaceutical product containing the same | National University Corporation, Gunma University (JP) | 2011-01-11 | — | — | US | disclosed |
| US-20100076224-A1 | NOVEL TRIHALOMETHIONINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING THE SAME | NATIONAL UNIVERSITY CORPORATION GUNMA UNIVERSITY (JP) | 2010-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100076224-A1 | NOVEL TRIHALOMETHIONINE DERIVATIVE AND PHARMACEUTICAL PRODUCT CONTAINING THE SAME | CTH, MTR, BHMT | CYP1A2 745/4885CYP2C9 367/4885CYP2C19 472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.