Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | APP | P05067 | 5/20 | 0.44 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | AGXT | P21549 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4159575 | 0.95 | ABCB1 (0.51) | NPC1RAB9APOLBSMN1; SMN2MAOB | |
| SCHEMBL4898090 | 0.83 | LTA4H (0.45) | ABCB1HTR1AIDO1 | |
| SCHEMBL5583748 | 0.81 | KDM4E (0.49) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL4684239 | 0.81 | MGAM (0.44) | NPC1RAB9ASMN1; SMN2HTR1AADRA1D | |
| SCHEMBL4153190 | 0.80 | ALDH1A1 (0.47) | NPC1RAB9APDE3BPDE3APDE10A | |
| Hydrochloric Acid SCHEMBL10371618 | 0.79 | KDM4E (0.51) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10530981 | 0.79 | RAB9A (0.54) | NPC1RAB9APOLBSMN1; SMN2ABCB1 | |
| SCHEMBL4140684 | 0.77 | ABCB1 (0.53) | NPC1RAB9AMAOBABCB1HTR1A | |
| SCHEMBL4152950 | 0.76 | RAB9A (0.50) | NPC1RAB9APOLBSMN1; SMN2MAOB | |
| SCHEMBL28980427 | 0.75 | PDE2A (0.47) | NPC1RAB9AAPPPOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280240-A2 | Cephalosporin derivatives, process for their preparation and antibacterial agents | Banyu Pharmaceutical Co., Ltd. (JP) | 1988-08-31 | — | — | EP | disclosed |