SCHEMBL5583748

SCHEMBL5583748

COc1ccnc(CO)c1OCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
BCHE P06276 8/20 0.48
MGAM O43451 1/20 0.47
GAA P10253 1/20 0.47
SI P14410 1/20 0.47
MGAM2 Q2M2H8 1/20 0.47
LMNA P02545 1/20 0.45
HSD17B10 Q99714 1/20 0.45
HTR1A P08908 1/20 0.45
ADRA1D P25100 1/20 0.45
ADRA1A P35348 1/20 0.45
ADRA1B P35368 1/20 0.45
PRMT5 O14744 1/20 0.43
PDE4D Q08499 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL10371618 0.98 KDM4E (0.51) KDM4EL3MBTL1BCHEMGAMGAA
SCHEMBL4898090 0.91 LTA4H (0.45) KDM4EL3MBTL1MGAMGAASI
SCHEMBL4684239 0.88 MGAM (0.44) L3MBTL1MGAMGAASIMGAM2
SCHEMBL4159575 0.88 ABCB1 (0.51) BCHEHTR1AADRA1DADRA1AADRA1B
Hydrochloric Acid SCHEMBL10370912 0.85 LMNA (0.46) KDM4EL3MBTL1BCHELMNAHTR1A
SCHEMBL17754130 0.83 LMNA (0.46) KDM4EL3MBTL1MGAMGAASI
SCHEMBL16740341 0.83 HTR1A (0.36) KDM4EL3MBTL1MGAMGAASI
SCHEMBL9281183 0.82 BCHE (0.55) KDM4EL3MBTL1BCHELMNAHTR1A
SCHEMBL4360270 0.81 KMT2A (0.42) KDM4EL3MBTL1BCHEMGAMGAA
SCHEMBL10247056 0.81 LMNA (0.47) KDM4EL3MBTL1MGAMGAASI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7183278-B1 Picolinamide derivative and harmful organism control agent comprising said picolinamide derivative as active component MEIJI SEIKA KAISHA, LTD. (JP) 2007-02-27 US disclosed
EP-1134214-A1 PICOLINAMIDE DERIVATIVES AND PEST CONTROLLERS CONTAINING THE SAME AS THE ACTIVE INGREDIENT MEIJI SEIKA KAISHA LTD. (JP) 2001-09-19 EP disclosed
US-5620995-A Substituted heterocyclic carboxyamides, their preparation and their use as pharmaceuticals HOECHST AKTIENGESELLSCHAFT (DE) 1997-04-15 US disclosed
CN-1126203-A Substituted heterocyclic carboxamides, their preparation and their use as pharmaceuticals HOECHST AG (DE) 1996-07-10 CN disclosed
EP-0661269-A1 Substituted heterocyclic carboxylic acid amides, their preparation and their use as medicaments HOECHST AKTIENGESELLSCHAFT (DE) 1995-07-05 EP disclosed
EP-0648209-A1 CONTRAST AGENTS FOR MR DIAGNOSIS Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1995-04-19 EP disclosed
WO-1994001406-A1 CONTRAST AGENTS FOR MR DIAGNOSIS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1994-01-20 WO disclosed
EP-0390842-A1 NOVEL BENZIMIDAZOLE DERIVATIVES Byk Gulden Lomberg Chemische Fabrik GmbH (DE) 1990-10-10 EP disclosed
WO-1989005299-A1 NOVEL BENZIMIDAZOLE DERIVATIVES BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1989-06-15 WO disclosed