Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | SI | P14410 | 3/20 | 0.44 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.44 |
| ▸ | ATP4A | P20648 | 1/20 | 0.44 |
| ▸ | ATP4B | P51164 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | RHEB | Q15382 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4898090 | 0.91 | LTA4H (0.45) | MGAMGAASIMGAM2ATP4A | |
| SCHEMBL5583748 | 0.88 | KDM4E (0.49) | MGAMGAASIMGAM2L3MBTL1 | |
| SCHEMBL4159575 | 0.88 | ABCB1 (0.51) | LTA4HHTR1AADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL10371618 | 0.87 | KDM4E (0.51) | MGAMGAASIMGAM2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL10373109 | 0.85 | MAPT (0.41) | LIPEMAPTMAPK1TDP1L3MBTL1 | |
| SCHEMBL4687273 | 0.84 | ALDH1A1 (0.53) | MAPTTDP1L3MBTL1RXRAATM | |
| SCHEMBL10917428 | 0.83 | MAPT (0.57) | ATP4AATP4BLIPEMAPTMAPK1 | |
| SCHEMBL4688192 | 0.81 | L3MBTL1 (0.50) | ATP4AATP4BLIPEMAPTMAPK1 | |
| SCHEMBL10678151 | 0.81 | NPC1 (0.50) | HTR1AADRA1DADRA1AADRA1BNPC1 | |
| SCHEMBL30963126 | 0.80 | RAB9A (0.42) | ATP4AATP4BMAPTMAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1973906-A1 | HYDROXYDIHYDROPYRIDOPY RAZINE-1,8-DIONES AND METHODS FOR INHIBITING HIV INTEGRASE | Virochem Pharma Inc. (CA) | 2008-10-01 | — | — | EP | disclosed |
| WO-2006066414-A1 | HYDROXYDIHYDROPYRIDOPY RAZINE-1,8-DIONES AND METHODS FOR INHIBITING HIV INTEGRASE | VIROCHEM PHARMA INC. (CA) | 2006-06-29 | — | — | WO | disclosed |
| EP-0390842-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1990-10-10 | — | — | EP | disclosed |
| WO-1989005299-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1989-06-15 | — | — | WO | disclosed |