Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.36 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4928553 | 0.88 | KIF11 (0.42) | KIF11ALDH1A1GLO1TSHRPTGS1 | |
| SCHEMBL1068350 | 0.77 | KIF11 (0.43) | KIF11ALDH1A1GLO1TSHRPTGS1 | |
| SCHEMBL22631543 | 0.74 | NOTUM (0.33) | KIF11PTGS1 | |
| SCHEMBL31093906 | 0.71 | KIF11 (0.65) | KIF11ALDH1A1GLO1TSHRPTPN1 | |
| SCHEMBL2138447 | 0.71 | KIF11 (0.65) | KIF11ALDH1A1GLO1TSHRPTPN1 | |
| SCHEMBL28222642 | 0.70 | KIF11 (0.70) | KIF11ALDH1A1GLO1TSHRPTPN1 | |
| SCHEMBL1064348 | 0.70 | KIF11 (0.40) | KIF11ALDH1A1PTPN1PTPN5CRHBP | |
| SCHEMBL4040861 | 0.70 | KIF11 (0.40) | KIF11ALDH1A1TSHRPTPN1PTPN5 | |
| SCHEMBL262125 | 0.69 | TSHR (0.36) | KIF11ALDH1A1TSHR | |
| SCHEMBL1069867 | 0.69 | ALDH1A1 (0.47) | KIF11ALDH1A1GLO1TSHRPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006886-A2 | AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV | BASF SE (DE) | 2011-01-20 | — | — | WO | disclosed |