SCHEMBL262125

SCHEMBL262125

FC(F)(F)c1[c]c(C(F)(F)F)ccc1

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPK1 P28482 1/20 0.33
KIF11 P52732 1/20 0.31
CES2 O00748 1/20 0.30
MGLL Q99685 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11504024 0.87 CA2 (0.31)
SCHEMBL15353486 0.84 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL148397 0.84 ALDH1A1 (0.31) TSHRALDH1A1
SCHEMBL1068722 0.82 ENPP3 (0.30)
SCHEMBL1067884 0.82 RAPGEF4 (0.31)
SCHEMBL6221220 0.82 TSHR (0.37) TSHRMAPK1
SCHEMBL260829 0.82 ENPP3 (0.30)
SCHEMBL1066627 0.78
SCHEMBL5951584 0.77
SCHEMBL8467075 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 764 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344695-A Hydroxyl-enriched cycloolefin copolymer long afterglow material and application thereof 重庆理工大学 2024-07-16 CN claimed
US-11807620-B2 Quinazolinone compounds and related compounds Plexium, Inc. (US) 2023-11-07 US claimed
CN-116693734-A Preparation method and application of trans-1, 2-poly-ocimene 湖北航天化学技术研究所 2023-09-05 CN claimed
US-20230001395-A1 Catalysts for Olefin Metathesis, Methods of Preparation, and Processes for the Use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-01-05 US claimed
CN-115385957-A Linear terphenyl aryl phosphine ligand and transition metal complex thereof 东莞市均成高新材料有限公司 2022-11-25 CN claimed
CN-114989519-A Application of cycloolefin polymer in long afterglow material 重庆理工大学 2022-09-02 CN claimed
CN-113461850-B Trans-1, 4-poly (4, 8-2-methyl-1, 3, 7-nonane triene) and preparation method thereof 中国科学院长春应用化学研究所 2022-03-29 CN claimed
CN-113461850-A Trans-1, 4-poly (4, 8-2-methyl-1, 3, 7-nonane triene) and preparation method thereof 中国科学院长春应用化学研究所 2021-10-01 CN claimed
CN-113444125-A Novel phosphoramidite ligand, preparation method thereof and application thereof in asymmetric carbonylation reaction 西北大学 2021-09-28 CN claimed
WO-2021072231-A1 CATALYSTS FOR OLEFIN METATHESIS, METHODS OF PREPARATION, AND PROCESSES FOR THE USE THEREOF EXXONMOBIL CHEMICAL PATENTS INC. (US) 2021-04-15 WO claimed
US-5932393-A Borate photoinitiators from monoboranes CIBA SPECIALTY CHEMICALS CORPORATION (US) 1999-08-03 US claimed
EP-0919571-A1 Catalyst composition comprising a reduced transition metal complex and a cocatalyst DSM N.V. (NL) 1999-06-02 EP claimed
EP-0627926-B1 PEPTIDYL DERIVATIVES AS INHIBITORS OF INTERLEUKIN-1$g(b) CONVERTING ENZYME MERCK & CO INC (US) 1998-08-05 EP claimed
EP-0557192-B1 Pyrethrinoid esters derived from 6-trifluoromethyl benzyl alcohol, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1996-08-21 EP claimed
EP-0272671-B1 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD (CH) 1994-03-16 EP claimed
EP-0557192-A1 Pyrethrinoid esters derived from 6-trifluoromethyl benzyl alcohol, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1993-08-25 EP claimed
US-5055451-A Prevent tissue damage SYNTEX INC. (US) 1991-10-08 US claimed
US-4845223-A FLUORESCENT PERYLENE DYES BASF AKTIENGESELLSCHAFT (DE) 1989-07-04 US claimed
EP-0272671-A2 Aryloxy and arylacyloxy methyl ketones as thiol protease inhibitors SANDOZ LTD. (CH) 1988-06-29 EP claimed
US-4125620-A HYPOTENSIVE BOEHRINGER INGELHEIM GMBH (DE) 1978-11-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807620-B2 Quinazolinone compounds and related compounds NQO2, COQ8A, PARK7 TSHR 4615/4885ALDH1A1 2127/4885MAPK1 2025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.