Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.36 |
| ▸ | IGF2BP2 | Q9Y6M1 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL534316 | 0.81 | PTPN1 (0.37) | KIF11ALDH1A1METAP2IGF2BP2PTPN1 | |
| SCHEMBL620577 | 0.75 | GPR3 (0.30) | GPR3 | |
| SCHEMBL3541755 | 0.75 | KIF11 (0.41) | KIF11ALDH1A1METAP2AURKATPX2 | |
| SCHEMBL27822799 | 0.75 | ALOX5 (0.37) | ALDH1A1 | |
| SCHEMBL2253244 | 0.73 | GPR3 (0.38) | KIF11METAP2AURKATPX2AKR1C2 | |
| SCHEMBL1069430 | 0.71 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL306823 | 0.71 | KIF11 (0.50) | KIF11AURKATPX2IGF2BP2CHRM5 | |
| SCHEMBL18293362 | 0.71 | KIF11 (0.50) | KIF11AURKATPX2IGF2BP2CHRM5 | |
| SCHEMBL27610712 | 0.71 | METAP2 (0.43) | KIF11METAP2CHRM5SCN9AGPR3 | |
| SCHEMBL5840598 | 0.71 | SLC13A5 (0.51) | KIF11DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011006886-A2 | AZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT XIV | BASF SE (DE) | 2011-01-20 | — | — | WO | disclosed |