Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | SCD | O00767 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.34 |
| ▸ | MAT2A | P31153 | 3/20 | 0.33 |
| ▸ | PDE2A | O00408 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9774917 | 0.91 | KCNH2 (0.38) | SCDMCHR1MAT2APDE2AEGFR | |
| SCHEMBL10684431 | 0.89 | HSD11B1 (0.36) | MCHR1MAT2AHTT | |
| SCHEMBL9774765 | 0.84 | CA2 (0.37) | CA2SCDMCHR1MAT2AEGFR | |
| SCHEMBL10679158 | 0.81 | GABRA2 (0.38) | CA2MCHR1PDE2AHTT | |
| SCHEMBL10676608 | 0.81 | PARK7 (0.35) | CA2SCDMCHR1EGFRLMNA | |
| SCHEMBL9774914 | 0.80 | CA2 (0.34) | CA2SCDMCHR1MAT2AEGFR | |
| SCHEMBL10059399 | 0.78 | MCHR1 (0.43) | CA2MCHR1HTTSMN1; SMN2 | |
| SCHEMBL10059743 | 0.77 | SMN1; SMN2 (0.56) | SCDLMNAHTTSMN1; SMN2 | |
| SCHEMBL9774928 | 0.76 | GABRA2 (0.38) | SCDPDE2AHTTSMN1; SMN2 | |
| SCHEMBL10676569 | 0.76 | MAPT (0.36) | PDE2ALMNAGAADAOIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | claimed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | claimed |
| US-4725607-A | MITICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-02-16 | — | — | US | disclosed |
| EP-0216541-A1 | Aryl pyridones | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1987-04-01 | — | — | EP | disclosed |