Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.55 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.55 |
| ▸ | ALDH1B1 | P30837 | 1/20 | 0.55 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.52 |
| ▸ | HPGD | P15428 | 5/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10602435 | 0.89 | HSD17B3 (0.53) | HSD17B3ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL12435277 | 0.84 | SLC18A1 (0.52) | HSD17B3ALDH1A1TSHRMAPTALDH1A2 | |
| SCHEMBL7255605 | 0.79 | HSD17B3 (0.65) | HSD17B3ALDH1A1TSHRMAPTALDH1A2 | |
| SCHEMBL15082519 | 0.76 | HSD17B3 (0.61) | HSD17B3ALDH1A1TSHRMAPTALDH1A2 | |
| SCHEMBL14578414 | 0.76 | PDE10A (0.48) | ALDH1A1TSHRKDM4EHPGDHSD17B10 | |
| SCHEMBL19002490 | 0.76 | ALDH1A1 (0.68) | HSD17B3ALDH1A1TSHRMAPTALDH1A2 | |
| SCHEMBL9431755 | 0.75 | STS (0.58) | NQO1 | |
| SCHEMBL10603419 | 0.75 | ALDH1A1 (0.60) | HSD17B3ALDH1A1TSHRKDM4EHPGD | |
| SCHEMBL15842598 | 0.74 | GABRP (0.50) | ALDH1A1KDM4EHPGDHSD17B10LMNA | |
| SCHEMBL14424526 | 0.74 | GABRP (0.50) | LMNAKMT2ATDP1NQO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4749798-A | ANTIINFLAMMATORY, ANTISWELLING | BOEHRINGER BIOCHEMIA ROBIN SPA (IT) | 1988-06-07 | — | — | US | disclosed |
| EP-0185319-A2 | Fluoro coumarins as antilymphoedema agents | BOEHRINGER MANNHEIM ITALIA S.P.A. (IT) | 1986-06-25 | — | — | EP | disclosed |