Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | YEATS4 | O95619 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.35 |
| ▸ | HPGD | P15428 | 4/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683685 | 1.00 | SMN1; SMN2 (0.38) | SMN1; SMN2KMT2AMEN1LMNAHRH3 | |
| SCHEMBL10682262 | 0.80 | ALDH1A1 (0.42) | SMN1; SMN2KMT2AMEN1LMNAHRH3 | |
| SCHEMBL9820846 | 0.77 | HRH3 (0.47) | LMNAHRH3NPC1HSD17B10HTT | |
| SCHEMBL10680602 | 0.76 | MAPK1 (0.41) | KMT2ALMNAHRH3NPC1YEATS4 | |
| SCHEMBL10678148 | 0.76 | YEATS4 (0.39) | KMT2ALMNANPC1YEATS4MAPK1 | |
| SCHEMBL10684339 | 0.74 | HRH3 (0.39) | SMN1; SMN2KMT2AMEN1HRH3NPC1 | |
| SCHEMBL10683557 | 0.74 | HRH3 (0.39) | SMN1; SMN2KMT2AMEN1HRH3NPC1 | |
| SCHEMBL19001110 | 0.74 | YEATS4 (0.62) | SMN1; SMN2KMT2AMEN1LMNANPC1 | |
| SCHEMBL19001105 | 0.74 | YEATS4 (0.62) | SMN1; SMN2KMT2AMEN1LMNANPC1 | |
| SCHEMBL10682744 | 0.72 | SIGMAR1 (0.38) | SMN1; SMN2KMT2ALMNAALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743602-A | AND CORRESPONDING FURANS, PYRROLES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-10 | — | — | US | disclosed |