Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10683557 | 1.00 | HRH3 (0.39) | HRH3NPC1HSD17B10CHRNB2CHRNB4 | |
| SCHEMBL9820846 | 0.78 | HRH3 (0.47) | HRH3NPC1HSD17B10CRHBPCRHR2 | |
| SCHEMBL10682399 | 0.77 | MITF (0.32) | KMT2AMEN1 | |
| SCHEMBL10685828 | 0.77 | FFAR1 (0.38) | HRH3KMT2AMEN1 | |
| SCHEMBL10684334 | 0.74 | SMN1; SMN2 (0.38) | HRH3NPC1HSD17B10KMT2AMEN1 | |
| SCHEMBL10683685 | 0.74 | SMN1; SMN2 (0.38) | HRH3NPC1HSD17B10KMT2AMEN1 | |
| SCHEMBL10685814 | 0.72 | SIGMAR1 (0.39) | HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL9820772 | 0.71 | NPC1 (0.44) | HRH3NPC1HSD17B10ALDH1A1SMN1; SMN2 | |
| SCHEMBL10678316 | 0.70 | MAPT (0.39) | KMT2AMEN1CYP2C19PKMMAPK1 | |
| SCHEMBL10682262 | 0.64 | ALDH1A1 (0.42) | HRH3NPC1HSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4743602-A | AND CORRESPONDING FURANS, PYRROLES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-05-10 | — | — | US | disclosed |