Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 14/20 | 0.46 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | USP5 | P45974 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681929 | 0.89 | CDC7 (0.42) | UCHL1UCHL3TGM2CASP3USP5 | |
| SCHEMBL10681150 | 0.88 | UCHL1 (0.50) | UCHL1GAAKDM4EHPGDHSD17B10 | |
| SCHEMBL10675823 | 0.86 | CDC7 (0.38) | UCHL1GAAHSD17B10MAPTMEN1 | |
| SCHEMBL10678457 | 0.85 | LMNA (0.40) | UCHL1GAAMAPTMEN1KMT2A | |
| SCHEMBL10674925 | 0.85 | ALDH1A1 (0.53) | GAAKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10677653 | 0.84 | UCHL1 (0.53) | UCHL1GAAKDM4EHPGDMAPT | |
| SCHEMBL10681743 | 0.84 | PDE3B (0.53) | UCHL1UCHL3TGM2CASP3USP5 | |
| SCHEMBL10680362 | 0.82 | SRD5A2 (0.48) | GAAKDM4EMAPTMEN1KMT2A | |
| SCHEMBL7383615 | 0.81 | PDE3B (0.46) | GAAKDM4EHPGDHSD17B10MAPT | |
| SCHEMBL10683067 | 0.79 | KDM4E (0.37) | UCHL1UCHL3TGM2CASP3USP5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |