Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | UCHL1 | P09936 | 5/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | UCHL3 | P15374 | 1/20 | 0.32 |
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 1/20 | 0.32 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10684915 | 0.89 | CDC7 (0.40) | DRD2TRPA1ALDH1A1CYP3A4TMIGD3 | |
| SCHEMBL10680809 | 0.86 | DRD2 (0.36) | KDM4EGAAHSD17B10HPGDDRD2 | |
| SCHEMBL10675710 | 0.85 | ALDH1A1 (0.51) | KDM4EGAAALDH1A1POLBPDE3B | |
| SCHEMBL10680981 | 0.85 | DRD2 (0.38) | GAADRD2TRPA1CYP3A4TMIGD3 | |
| SCHEMBL7376126 | 0.81 | PDE3B (0.44) | KDM4EGAAHSD17B10HPGDDRD2 | |
| SCHEMBL10681150 | 0.80 | UCHL1 (0.50) | KDM4EGAAHSD17B10HPGDALDH1A1 | |
| SCHEMBL10684520 | 0.79 | UCHL1 (0.46) | KDM4EGAAHSD17B10HPGDCYP3A4 | |
| SCHEMBL10681743 | 0.79 | PDE3B (0.53) | KDM4EGAAHSD17B10HPGDALDH1A1 | |
| SCHEMBL10675744 | 0.79 | DRD2 (0.38) | KDM4EHPGDDRD2TRPA1ALDH1A1 | |
| SCHEMBL10677653 | 0.77 | UCHL1 (0.53) | KDM4EGAAHPGDALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4769380-A | Cardiotonic 5-benzoyl-1,2-dihydro-2-oxo-3-pyridinecarboxylates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1988-09-06 | — | — | US | disclosed |