Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | GSR | P00390 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10700898 | 0.81 | ALDH1A1 (0.41) | MEN1KMT2AALDH1A1NPC1RAB9A | |
| SCHEMBL7567436 | 0.80 | MAOB (0.51) | MAOBHDAC1HDAC8HDAC6GSR | |
| SCHEMBL410414 | 0.76 | ALDH1A1 (0.45) | MAOBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1873122 | 0.74 | NFKB1 (0.42) | HDAC1HDAC8HDAC6MEN1KMT2A | |
| SCHEMBL10164856 | 0.73 | MAOB (0.46) | MAOBHDAC1HDAC8HDAC6GSR | |
| SCHEMBL5474595 | 0.73 | LMNA (0.53) | MAOBMEN1KMT2AMAPTNPC1 | |
| SCHEMBL5474591 | 0.73 | LMNA (0.53) | MAOBMEN1KMT2AMAPTNPC1 | |
| Chlorobenzene SCHEMBL28079345 | 0.72 | XPO1 (0.40) | GSRMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL28243582 | 0.72 | CYP1A2 (0.36) | KMT2AALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL12643730 | 0.72 | ALDH1A1 (0.44) | MAOBHDAC1HDAC8HDAC6GSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279151-A1 | Pertussis toxin polypeptide and its uses | TRION FORSKNING- OCH UTVECKLINGS AKTIEBOLAG (SE) | 1988-08-24 | — | — | EP | disclosed |