Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | SGPL1 | O95470 | 4/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685328 | 0.84 | CYP26A1 (0.50) | SIGMAR1CYP26A1CYP19A1HTR1ADDB1 | |
| SCHEMBL10366186 | 0.80 | HTR1A (0.36) | SIGMAR1HTR1ATSHRDDB1CRBN | |
| SCHEMBL10685552 | 0.80 | TSHR (0.34) | TSHRDDB1CRBNFFAR1PPARG | |
| SCHEMBL10688765 | 0.78 | MTNR1A (0.41) | FFAR1PPARG | |
| SCHEMBL10686431 | 0.78 | PPARG (0.52) | S1PR1SGPL1CYP26A1CYP19A1FFAR1 | |
| SCHEMBL10681257 | 0.77 | MTNR1A (0.43) | SIGMAR1TSHRFFAR1PPARG | |
| SCHEMBL10690190 | 0.74 | PPARG (0.52) | CYP19A1FFAR1PPARG | |
| SCHEMBL10686465 | 0.72 | PPARG (0.50) | SIGMAR1TSHRFFAR1PPARG | |
| SCHEMBL10684731 | 0.72 | TSHR (0.36) | TSHRDDB1CRBNFFAR1 | |
| SCHEMBL10685146 | 0.69 | PIM1 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |