Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 12/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10681257 | 0.91 | MTNR1A (0.43) | MTNR1AFFAR1PPARG | |
| SCHEMBL10685552 | 0.89 | TSHR (0.34) | MTNR1AFFAR1FNTAFNTBPPARG | |
| SCHEMBL10687997 | 0.81 | PPARG (0.48) | MTNR1AMTNR1BFFAR1PPARGMAPT | |
| SCHEMBL10688715 | 0.80 | ALDH1A1 (0.46) | KDM4ELMNAMAPT | |
| SCHEMBL10685328 | 0.80 | CYP26A1 (0.50) | — | |
| SCHEMBL10685155 | 0.78 | S1PR1 (0.40) | FFAR1PPARG | |
| SCHEMBL10366186 | 0.77 | HTR1A (0.36) | FFAR1 | |
| SCHEMBL10684731 | 0.76 | TSHR (0.36) | FFAR1MAPT | |
| SCHEMBL10685179 | 0.74 | BRS3 (0.32) | KDM4ELMNAMAPT | |
| SCHEMBL10687991 | 0.72 | HPGD (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |