Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | ALPL | P05186 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10688965 | 0.81 | RAB9A (0.46) | BACE1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9375675 | 0.81 | ASIC3 (0.59) | BACE1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL10689287 | 0.81 | KMO (0.53) | BACE1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL10688267 | 0.77 | NPC1 (0.53) | MAPTNPC1RAB9ALTA4HKDM4E | |
| SCHEMBL1797508 | 0.75 | ASIC3 (0.67) | BACE1MAPTNPC1RAB9ALTA4H | |
| SCHEMBL1765925 | 0.74 | BACE1 (0.48) | BACE1KDM4EALDH1A1KMT2A | |
| SCHEMBL6412343 | 0.73 | PIK3CD (0.40) | BACE1MAPTNPC1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL2132244 | 0.73 | ASIC3 (0.64) | BACE1MAPTNPC1RAB9ALTA4H | |
| SCHEMBL28587746 | 0.73 | SUCNR1 (0.47) | MAPTNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL1752781 | 0.72 | SLC6A2 (0.50) | BACE1MAPTNPC1RAB9ALTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108558869-B | For treating the compound and its preparation of liver cancer | 西安培华学院 | 2019-04-09 | — | — | CN | disclosed |
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |