Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | CSF1R | P07333 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10686121 | 0.82 | ATP4A (0.46) | POLBRAB9ASMN1; SMN2HCRTR1TP53 | |
| Iodide SCHEMBL10692950 | 0.81 | HCRTR1 (0.33) | POLBRAB9ASMN1; SMN2HCRTR1TP53 | |
| SCHEMBL10693490 | 0.76 | RAB9A (0.36) | POLBRAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL9747654 | 0.70 | ATP4A (0.47) | MAPK1 | |
| SCHEMBL9747208 | 0.69 | ATP4A (0.56) | KDM4EJAK2JAK3PTK2MAPK1 | |
| SCHEMBL9747064 | 0.69 | ATP4A (0.60) | SMN1; SMN2HTTMAPTMAPK1 | |
| SCHEMBL5749903 | 0.67 | KDM4E (0.49) | POLBRAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10613089 | 0.65 | CYP3A4 (0.46) | POLBRAB9ASMN1; SMN2KDM4ENPC1 | |
| SCHEMBL10689756 | 0.65 | ATP4A (0.55) | SMN1; SMN2HTTROCK1MAPTMAPK1 | |
| SCHEMBL9091033 | 0.64 | KDM4E (0.42) | POLBSMN1; SMN2KDM4EALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738967-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-04-19 | — | — | US | disclosed |
| US-4686227-A | Imidazoisoquinoline compounds useful as anti-ulcerative agents | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1987-08-11 | — | — | US | disclosed |
| EP-0165545-A2 | Imidazoisoquinoline compounds and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1985-12-27 | — | — | EP | disclosed |