Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HK1 | P19367 | 1/20 | 0.53 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | METAP2 | P50579 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10687121 | 0.82 | KDM4E (0.51) | MAPTBACE1IDO1ASIC3MEN1 | |
| SCHEMBL10689759 | 0.82 | RAB9A (0.47) | RAB9AALDH1A1BACE1IDO1METAP2 | |
| SCHEMBL9375675 | 0.80 | ASIC3 (0.59) | MAPTRAB9AALDH1A1HPGDBACE1 | |
| SCHEMBL10688611 | 0.78 | MAP4K4 (0.53) | BACE1KMT2AKDM4E | |
| SCHEMBL27897653 | 0.77 | CYP1A2 (0.47) | MAPTRAB9AALDH1A1HPGDHK1 | |
| SCHEMBL17460455 | 0.76 | RAB9A (0.58) | MAPTRAB9AALDH1A1HPGDHK1 | |
| SCHEMBL29473316 | 0.76 | RAB9A (0.58) | MAPTRAB9AALDH1A1HPGDHK1 | |
| SCHEMBL17174152 | 0.75 | RAB9A (0.50) | MAPTRAB9AALDH1A1HPGDHK1 | |
| SCHEMBL10689287 | 0.73 | KMO (0.53) | MAPTRAB9AALDH1A1HPGDBACE1 | |
| SCHEMBL30923427 | 0.72 | GABRA1 (0.50) | MAPTRAB9AALDH1A1HPGDHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4720500-A | N-1,8-naphthyridin-2-yl amides useful as immunostimulants | RHONE-POULENC SANTE (FR) | 1988-01-19 | — | — | US | disclosed |