SCHEMBL10690277

SCHEMBL10690277

O=C1OC(=O)c2cc(OC(=C(C(F)(C(F)(F)F)C(F)(F)F)C(F)(C(F)(F)F)C(F)(F)F)C(F)(F)F)ccc21

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.33
CA2 P00918 1/20 0.32
ALOX15 P16050 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12337780 0.72 ALOX15 (0.43) ALDH1A1CA2ALOX15TDP1
SCHEMBL10697499 0.71 ALDH1A1 (0.47) ALDH1A1TDP1
SCHEMBL9314112 0.71 ALOX15 (0.39) ALDH1A1CA2ALOX15TDP1
SCHEMBL9492695 0.69 CA2 (0.33) ALDH1A1CA2
SCHEMBL3320871 0.69 ALOX15 (0.40) ALDH1A1CA2ALOX15TDP1
SCHEMBL4474802 0.69 CA12 (0.51) ALDH1A1TDP1
SCHEMBL6825123 0.69 HSD17B10 (0.44) ALDH1A1CA2ALOX15
SCHEMBL9680716 0.69 PRSS1 (0.50) ALDH1A1TDP1
SCHEMBL4204276 0.68 KMT2A (0.51) ALDH1A1CA2TDP1
SCHEMBL8968025 0.68 KMT2A (0.48) ALDH1A1CA2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0137716-B1 OPTICAL ADHESIVE COMPOSITION NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-12-14 EP claimed
US-4637939-A Optical adhesive composition NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1987-01-20 US claimed
US-4591627-A Optical adhesive composition NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1986-05-27 US claimed
EP-0137716-A2 Optical adhesive composition NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1985-04-17 EP claimed
JP-61151044-A None JP disclosed
EP-0137716-B1 OPTICAL ADHESIVE COMPOSITION NIPPON TELEGRAPH AND TELEPHONE CORPORATION (JP) 1988-12-14 EP disclosed
US-4637939-A Optical adhesive composition NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1987-01-20 US disclosed
JP-S61151044-A COATING GLASS NIPPON TELEGR & TELEPH CORP <NTT> 1986-07-09 JP disclosed
US-4591627-A Optical adhesive composition NIPPON TELEGRAPH & TELEPHONE PUBLIC CORPORATION (JP) 1986-05-27 US disclosed