Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14068217 | 0.91 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL3969663 | 0.88 | ADAM17 (0.50) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL8011907 | 0.85 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL2263155 | 0.83 | RAB9A (0.47) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL825205 | 0.83 | MAOA (0.54) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL12353235 | 0.82 | KDM4E (0.45) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL8754251 | 0.79 | ALDH1A1 (0.56) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL851166 | 0.79 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL8204708 | 0.77 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT | |
| SCHEMBL5090074 | 0.77 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2LMNACYP2A6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0273280-A2 | Condensation polymer containing the residue of a poly-methine compound and shaped articles produced therefrom | EASTMAN CHEMICAL COMPANY (US) | 1988-07-06 | — | — | EP | disclosed |
| US-4749774-A | UNSATURATED POLYESTERS | EASTMAN KODAK COMPANY (US) | 1988-06-07 | — | — | US | disclosed |