Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | GFER | P55789 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | VCP | P55072 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10691153 | 0.88 | LMNA (0.48) | LMNAHPGDFFAR1KDM4EGFER | |
| SCHEMBL10692209 | 0.88 | NPC1 (0.60) | LMNAHPGDFFAR1KMT2AMEN1 | |
| SCHEMBL8547416 | 0.81 | MAPT (0.41) | LMNAHPGDKMT2AMEN1NPC1 | |
| SCHEMBL10689661 | 0.78 | ALDH1A1 (0.60) | LMNAHPGDFFAR1KDM4EKMT2A | |
| SCHEMBL10692046 | 0.77 | NPC1 (0.63) | LMNAFFAR1KMT2AMEN1NPC1 | |
| SCHEMBL10691191 | 0.76 | ALDH1A1 (0.40) | LMNAKDM4EKMT2AMEN1NPC1 | |
| SCHEMBL9749252 | 0.76 | GAA (0.51) | LMNAHPGDKDM4EKMT2AMEN1 | |
| SCHEMBL10691483 | 0.76 | FFAR1 (0.58) | LMNAHPGDFFAR1KMT2AMEN1 | |
| SCHEMBL8546674 | 0.76 | SMN1; SMN2 (0.42) | LMNAHPGDKDM4EGFERKMT2A | |
| SCHEMBL8551360 | 0.75 | ALDH1A1 (0.46) | HPGDKDM4EALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |