Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CDK9 | P50750 | 1/20 | 0.44 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.41 |
| ▸ | TUBB | P07437 | 1/20 | 0.41 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.41 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.41 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9817680 | 0.75 | LMNA (0.61) | NAPRTHSD17B10KMT2AMEN1POLB | |
| SCHEMBL12629111 | 0.70 | ALDH1A1 (0.51) | KMT2AMEN1TSHRSLC6A2LMNA | |
| SCHEMBL9304492 | 0.70 | TSHR (0.54) | NAPRTHSD17B10KMT2AMEN1TP53 | |
| SCHEMBL14817483 | 0.68 | NAPRT (0.53) | NAPRTHSD17B10KMT2AMEN1POLB | |
| SCHEMBL22110225 | 0.68 | FAAH (0.50) | NAPRTHSD17B10KMT2AMEN1POLB | |
| SCHEMBL8052548 | 0.68 | LMNA (0.48) | NAPRTHSD17B10KMT2AMEN1POLB | |
| SCHEMBL13830839 | 0.67 | TSHR (0.50) | NAPRTHSD17B10KMT2AMEN1TP53 | |
| SCHEMBL28667446 | 0.67 | SMN1; SMN2 (0.50) | NAPRTHSD17B10KMT2AMEN1TP53 | |
| SCHEMBL1522066 | 0.67 | NAPRT (0.52) | NAPRTHSD17B10KMT2AMEN1POLB | |
| SCHEMBL106428 | 0.67 | SPHK1 (0.50) | NAPRTHSD17B10KMT2AMEN1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4772694-A | Chiral 3-(1,2,5-trisubstituted imidazolidinone) azetidinone antibiotic intermediates | ELI LILLY AND COMPANY (US) | 1988-09-20 | — | — | US | disclosed |