Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | STS | P08842 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | LTB4R | Q15722 | 8/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 8/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.36 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10690807 | 0.83 | PPARG (0.50) | CA2PPARGPPARAFFAR1 | |
| SCHEMBL10690582 | 0.77 | PPARG (0.48) | CA2PPARGPPARAFFAR1 | |
| SCHEMBL31558350 | 0.72 | LTB4R (0.53) | LTB4RLTB4R2 | |
| SCHEMBL10686384 | 0.72 | PPARG (0.52) | CA2PPARGPPARAFFAR1 | |
| SCHEMBL7243217 | 0.70 | SLC6A9 (0.55) | LTB4RLTB4R2 | |
| SCHEMBL7450732 | 0.67 | CA2 (0.51) | CA2PPARGPPARDPPARADDB1 | |
| SCHEMBL22480924 | 0.67 | CA2 (0.60) | CA2PPARGPPARDPPARADDB1 | |
| SCHEMBL7450830 | 0.67 | CA2 (0.51) | CA2PPARGPPARDPPARADDB1 | |
| SCHEMBL7251512 | 0.66 | ACHE (0.51) | — | |
| SCHEMBL6570475 | 0.66 | CA2 (1.00) | CA2PPARGPPARDPPARADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4738972-A | Hypoglycemic thiazolidinediones | PFIZER INC. (US) | 1988-04-19 | — | — | US | disclosed |