Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10685537 | 0.85 | TSHR (0.39) | TSHRALDH1A1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10688579 | 0.84 | LDHA (0.40) | TSHRALDH1A1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10689934 | 0.82 | LMNA (0.40) | TSHRALDH1A1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10690648 | 0.79 | TSHR (0.41) | TSHRALDH1A1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10691483 | 0.78 | FFAR1 (0.58) | ALDH1A1SMN1; SMN2MAPTGAANPC1 | |
| SCHEMBL18256147 | 0.75 | GAA (0.43) | ALDH1A1HSD17B10MAPTGAANPC1 | |
| SCHEMBL8550459 | 0.74 | ALDH1A1 (0.34) | ALDH1A1HSD17B10MAPTGAANPC1 | |
| SCHEMBL1540434 | 0.72 | HTT (0.51) | ALDH1A1HSD17B10MAPTHTT | |
| SCHEMBL10685599 | 0.72 | HSD17B10 (0.40) | TSHRALDH1A1HSD17B10SMN1; SMN2MAPT | |
| SCHEMBL10694025 | 0.72 | APEX1 (0.53) | TSHRALDH1A1HSD17B10SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4762848-A | IMMUNE SYSTEM STIMULANTS, CYTOSTATIC AGENTS | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-08-09 | — | — | US | disclosed |