Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKDC | P78527 | 2/20 | 0.64 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.64 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.64 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.64 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | STAT1 | P42224 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9416202 | 0.88 | ALDH1A1 (0.73) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL10692118 | 0.86 | NPC1 (0.71) | KDM4ESMN1; SMN2ALDH1A1AKR1C3HPGD | |
| SCHEMBL3322530 | 0.86 | NPC1 (0.71) | KDM4ESMN1; SMN2ALDH1A1AKR1C3HPGD | |
| SCHEMBL50238 | 0.85 | SMN1; SMN2 (0.74) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL6207977 | 0.84 | PRKDC (0.59) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9827103 | 0.83 | PRKDC (0.55) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL10396068 | 0.82 | PRKDC (0.76) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2742813 | 0.82 | NPC1 (0.66) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL2323487 | 0.81 | ALDH1A1 (0.64) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL18492962 | 0.80 | PRKDC (0.62) | PRKDCPIK3CDPIK3CAPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388953-A1 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-12-08 | — | — | US | disclosed |
| US-9535347-B2 | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2017-01-03 | — | — | US | disclosed |
| US-20140363759-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2014-12-11 | — | — | US | disclosed |
| US-20140363759-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KK (JP) | 2014-12-11 | — | — | US | disclosed |
| US-8841052-B2 | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2014-09-23 | — | — | US | disclosed |
| US-8841052-B2 | Electrophotographic photosensitive member, process cartridge and electrophotographic apparatus | CANON KABUSHIKI KAISHA (JP) | 2014-09-23 | — | — | US | disclosed |
| US-20140141362-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2014-05-22 | — | — | US | disclosed |
| US-20140141362-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2014-05-22 | — | — | US | disclosed |
| US-20130137023-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2013-05-30 | — | — | US | disclosed |
| US-20130137023-A1 | ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE AND ELECTROPHOTOGRAPHIC APPARATUS | CANON KABUSHIKI KAISHA (JP) | 2013-05-30 | — | — | US | disclosed |
| US-4748148-A | Recording system utilizing phthalide derivatives as colorless chromogenic material | NEW OJI PAPER CO., LTD. (JP) | 1988-05-31 | — | — | US | disclosed |
| US-4641160-A | Recording system utilizing phthalide derivatives as colorless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD. (JP) | 1987-02-03 | — | — | US | disclosed |
| EP-0127203-A1 | New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material | KANZAKI PAPER MANUFACTURING CO., LTD (JP) | 1984-12-05 | — | — | EP | disclosed |
| EP-0062544-A1 | New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material | KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) | 1982-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388953-A1 | COMPOUNDS WITH ANTIMICROBIAL ACTIVITY | MPO, MRPL21, ELANE | PRKDC 991/4885PIK3CD 3067/4885PIK3CA 3312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.