SCHEMBL472318

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL8193682	0.91	EGFR (0.69)	HCAR3EGFRERBB2SMN1; SMN2CA12
	SCHEMBL472266	0.89	EGFR (0.58)	EGFRERBB2SMN1; SMN2CA12CA2
	SCHEMBL9313948	0.87	HCAR3 (0.47)	HCAR3EGFRERBB2SMN1; SMN2CA12
	SCHEMBL11373304	0.87	EGFR (0.56)	EGFRERBB2SMN1; SMN2CA12CA2
	SCHEMBL472292	0.87	EGFR (0.53)	EGFRERBB2ALDH1A1TP53TSHR
	SCHEMBL14558227	0.86	SMN1; SMN2 (0.47)	HCAR3EGFRERBB2SMN1; SMN2CA12
	SCHEMBL10690897	0.86	EGFR (0.57)	HCAR3EGFRERBB2SMN1; SMN2CA12
	SCHEMBL2498524	0.86	EGFR (0.57)	HCAR3EGFRERBB2RAB9AALDH1A1
	SCHEMBL1134696	0.85	PTGES (0.54)	EGFRERBB2ALDH1A1TP53TSHR
	SCHEMBL472312	0.85	PTGES (0.54)	EGFRERBB2ALDH1A1TP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.