Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MPO | P05164 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2759569 | 0.79 | P2RX7 (0.39) | P2RX7KMT2AMEN1PTGS2KDM4E | |
| SCHEMBL84991 | 0.79 | KDM4E (0.43) | P2RX7KMT2APTGS2KDM4ECYP1A2 | |
| SCHEMBL13764331 | 0.79 | ALDH1A1 (0.46) | P2RX7KMT2AMEN1PTGS2KDM4E | |
| SCHEMBL729640 | 0.77 | L3MBTL1 (0.50) | KMT2AMEN1MMP2PTGS2PTGS1 | |
| SCHEMBL134193 | 0.74 | MEN1 (0.34) | P2RX7HSP90AA1KMT2AMEN1MMP2 | |
| SCHEMBL134192 | 0.72 | MEN1 (0.34) | KMT2AMEN1MMP2MMP14 | |
| SCHEMBL14080697 | 0.71 | CA2 (0.47) | P2RX7HSP90AA1CA1CA9CA12 | |
| SCHEMBL27564370 | 0.71 | HSP90AA1 (0.39) | P2RX7HSP90AA1GRM4KDM4ECTNNB1 | |
| SCHEMBL29579947 | 0.71 | HSP90AA1 (0.39) | P2RX7HSP90AA1GRM4KDM4ECTNNB1 | |
| SCHEMBL136276 | 0.70 | MEN1 (0.40) | P2RX7KMT2AMEN1MMP2MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4741760-A | Pyrimidine derivatives having a herbicidal action and an action regulating plant growth | CIBA-GEIGY CORPORATION (US) | 1988-05-03 | — | — | US | disclosed |