Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822676 | 0.96 | KCNH2 (0.43) | KCNH2TGFBR1PDE10ASMN1; SMN2 | |
| SCHEMBL10690694 | 0.91 | KCNH2 (0.35) | KCNH2TGFBR1PDE10A | |
| SCHEMBL9823067 | 0.81 | TGFBR1 (0.32) | TGFBR1 | |
| SCHEMBL7147211 | 0.73 | KCNH2 (0.62) | KCNH2PDE10ACYP19A1 | |
| SCHEMBL10693416 | 0.71 | KCNH2 (0.38) | KCNH2TGFBR1 | |
| SCHEMBL248521 | 0.70 | KCNH2 (0.95) | KCNH2CYP19A1 | |
| SCHEMBL10691008 | 0.69 | AOC3 (0.35) | KCNH2TGFBR1PDE10A | |
| SCHEMBL10748780 | 0.69 | KDM4E (0.50) | TGFBR1TP53MAPTSMN1; SMN2 | |
| SCHEMBL24973117 | 0.68 | KCNH2 (1.00) | KCNH2CYP19A1 | |
| SCHEMBL10790586 | 0.68 | KCNH2 (1.00) | KCNH2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217552-B1 | NOVEL PYRIDINE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND A PLANT DISEASE PROTECTANT CONTAINING THEM AS THE ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | disclosed |
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |