Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.30 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.30 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.30 |
| ▸ | KDM5A | P29375 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822971 | 0.96 | KCNH2 (0.49) | KCNH2TGFBR1SMN1; SMN2PDE10A | |
| SCHEMBL10690694 | 0.92 | KCNH2 (0.35) | KCNH2TGFBR1PDE10APIK3CDPIK3R1 | |
| SCHEMBL9823067 | 0.82 | TGFBR1 (0.32) | TGFBR1TLR7PIK3CDPIK3R1PIK3CA | |
| SCHEMBL10693416 | 0.74 | KCNH2 (0.38) | KCNH2TGFBR1PIK3CAPIK3CB | |
| SCHEMBL10749061 | 0.72 | NR1H3 (0.32) | NPY2RNR1H3ADORA3 | |
| SCHEMBL10691008 | 0.70 | AOC3 (0.35) | KCNH2TGFBR1PDE10A | |
| SCHEMBL10748780 | 0.70 | KDM4E (0.50) | TGFBR1SMN1; SMN2KDM4C | |
| SCHEMBL1404092 | 0.69 | KCNH2 (0.83) | KCNH2TLR7NOS2 | |
| SCHEMBL8250521 | 0.69 | KCNH2 (0.58) | KCNH2TLR7NOS2 | |
| SCHEMBL7147211 | 0.68 | KCNH2 (0.62) | KCNH2PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217552-B1 | NOVEL PYRIDINE DERIVATIVES, METHOD FOR PRODUCTION THEREOF AND A PLANT DISEASE PROTECTANT CONTAINING THEM AS THE ACTIVE INGREDIENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | claimed |
| JP-62149673-A | — | — | None | — | — | JP | disclosed |
| US-4769376-A | Certain tri- or tetra-substituted pyridyl-1,2,4-triazoles useful as fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1988-09-06 | — | — | US | disclosed |
| JP-S62149673-A | PYRIDINE DERIVATIVE, PRODUCTION THEREOF AND PLANT BLIGHT CONTROLLING AGENT CONTAINING SAID DERIVATIVE AS ACTIVE COMPONENT | SUMITOMO CHEM CO LTD | 1987-07-03 | — | — | JP | disclosed |
| EP-0217552-A2 | Novel pyridine derivatives, method for production thereof and a plant disease protectant containing them as the active ingredient | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-04-08 | — | — | EP | disclosed |