SCHEMBL10691214

SCHEMBL10691214

CC(C)C(=O)N(C)c1cccc(CC(Br)Br)n1

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ACACB O00763 1/20 0.33
MLYCD O95822 1/20 0.32
MMP9 P14780 1/20 0.32
NPSR1 Q6W5P4 1/20 0.31
HPGD P15428 1/20 0.31
CYP1A2 P05177 1/20 0.30
ITGB1 P05556 1/20 0.30
ITGA5 P08648 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6482760 0.85 MLYCD (0.33) ACACBMLYCDMMP9NPSR1CYP1A2
SCHEMBL6484238 0.78 MLYCD (0.34) MLYCD
SCHEMBL7656856 0.77 CLK1 (0.38) MLYCDMMP9HPGD
SCHEMBL6482424 0.75 RAB9A (0.40) MLYCDCYP1A2
SCHEMBL4072992 0.69 ALDH1A1 (0.34) ACACBNPSR1HPGDITGB1ITGA5
SCHEMBL4073680 0.68 NPSR1 (0.35) NPSR1
SCHEMBL26763994 0.67 LIPE (0.50) NPSR1
SCHEMBL28746530 0.67 NCF1 (0.56) NPSR1HPGDCYP1A2
SCHEMBL20890494 0.66 PARP1 (0.40) ACACBNPSR1CYP1A2
SCHEMBL4065110 0.66 NPSR1 (0.36) NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4772619-A ANTIULCER AGENTS G. D. SEARLE & CO. (US) 1988-09-20 US disclosed