SCHEMBL10691453

SCHEMBL10691453

CN(C)c1cc(C(=O)O)c(C(=O)c2ccccc2)cc1Cl

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.49
AKR1C3 P42330 2/20 0.47
NR4A1 P22736 1/20 0.45
GABRP O00591 1/20 0.45
GABRD O14764 1/20 0.45
GABRA1 P14867 1/20 0.45
GABRB1 P18505 1/20 0.45
GABRG2 P18507 1/20 0.45
GABRB3 P28472 1/20 0.45
GABRA5 P31644 1/20 0.45
GABRA3 P34903 1/20 0.45
GABRA2 P47869 1/20 0.45
GABRB2 P47870 1/20 0.45
GABRA4 P48169 1/20 0.45
GABRE P78334 1/20 0.45
GABRA6 Q16445 1/20 0.45
GABRG1 Q8N1C3 1/20 0.45
GABRG3 Q99928 1/20 0.45
GABRQ Q9UN88 1/20 0.45
GLA P06280 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8784827 0.84 KDM4E (0.61) KDM4EAKR1C3NR4A1HPGDHSD17B10
SCHEMBL10697549 0.83 KDM4E (0.50) KDM4EAKR1C3GABRPGABRDGABRA1
SCHEMBL10694304 0.81 RAB9A (0.48) KDM4EHPGDNPC1RAB9AHSD17B10
SCHEMBL10694952 0.79 LMNA (0.51) KDM4EAKR1C3GLAHPGDNPC1
SCHEMBL10695457 0.77 KDM4E (0.67) KDM4EAKR1C3GLAHPGDNPC1
SCHEMBL6641207 0.77 FABP4 (0.45) KDM4EAKR1C3GLAHPGDALDH1A1
SCHEMBL6637829 0.77 ACLY (0.46) KDM4EAKR1C3GLAHPGDHSD17B10
SCHEMBL6014019 0.76 AKR1C3 (0.71) KDM4EAKR1C3NR4A1HSD17B10CDC25A
SCHEMBL15793780 0.76 AKR1C3 (0.71) KDM4EAKR1C3NR4A1HSD17B10CDC25A
SCHEMBL6056968 0.76 AKR1C3 (0.71) KDM4EAKR1C3NR4A1HSD17B10CDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4748148-A Recording system utilizing phthalide derivatives as colorless chromogenic material NEW OJI PAPER CO., LTD. (JP) 1988-05-31 US disclosed
US-4641160-A Recording system utilizing phthalide derivatives as colorless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD. (JP) 1987-02-03 US disclosed
EP-0127203-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING CO., LTD (JP) 1984-12-05 EP disclosed
EP-0062544-A1 New phthalide derivatives, process for preparing the same and recording system utilizing the same as colourless chromogenic material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1982-10-13 EP disclosed