Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692809 | 0.80 | HTR6 (0.32) | LMNA | |
| SCHEMBL10694766 | 0.78 | APP (0.35) | LMNA | |
| SCHEMBL10335817 | 0.68 | RAD51 (0.33) | — | |
| SCHEMBL9079841 | 0.67 | EGFR (0.41) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL11701352 | 0.66 | RAPGEF4 (0.43) | KDM4EALDH1A1GAAMAPT | |
| SCHEMBL11233324 | 0.66 | CA12 (0.40) | KDM4ELMNAGAAMAPT | |
| SCHEMBL10692298 | 0.64 | FBP1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL10691575 | 0.64 | RAPGEF4 (0.39) | KDM4EALDH1A1GAAMAPT | |
| SCHEMBL19465710 | 0.62 | CTDSP1 (0.40) | KDM4EALDH1A1LMNAGAAMAPT | |
| SCHEMBL9717209 | 0.61 | RAPGEF4 (0.42) | KDM4EALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |