Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10692809 | 0.92 | HTR6 (0.32) | APPHTR6CA2RAD51LMNA | |
| SCHEMBL10691584 | 0.78 | KDM4E (0.32) | LMNA | |
| SCHEMBL10335817 | 0.75 | RAD51 (0.33) | RAD51 | |
| SCHEMBL9079841 | 0.74 | EGFR (0.41) | CA2RAD51LMNABLM | |
| SCHEMBL11233324 | 0.67 | CA12 (0.40) | CA2LMNA | |
| SCHEMBL5170316 | 0.66 | APP (0.48) | APPHTR6LMNASLC6A6CYP2C19 | |
| SCHEMBL1805939 | 0.65 | CA2 (0.42) | HTR6CA2LMNACYP2C19 | |
| SCHEMBL11479053 | 0.65 | RAPGEF4 (0.44) | CA2 | |
| SCHEMBL10693379 | 0.63 | APP (0.33) | APP | |
| SCHEMBL10694725 | 0.63 | RAPGEF4 (0.40) | APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785099-A | FIBER-REACTIVE DYES FOR CELLULOSE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-15 | — | — | US | disclosed |
| EP-0229339-A2 | Water soluble triphene dioxazine compounds, their starting compounds containing sulphonyl groups, process for their preparation and use of the triphene dioxazines as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-07-22 | — | — | EP | disclosed |