Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | MMP1 | P03956 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9733951 | 0.85 | KMT2A (0.51) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL4674082 | 0.81 | KMT2A (0.51) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL10793843 | 0.81 | RAB9A (0.43) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL11305905 | 0.79 | CA1 (0.56) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL1108994 | 0.78 | MMP1 (0.70) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL377282 | 0.78 | LIPE (0.51) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL9711102 | 0.75 | MAPT (0.53) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL17884768 | 0.74 | ESRRB (0.62) | MAPTALDH1A1MMP1SMN1; SMN2 | |
| SCHEMBL4257673 | 0.74 | NPC1 (0.70) | MAPTLMNAHTTKMT2AALDH1A1 | |
| SCHEMBL3920495 | 0.74 | ALDH1A1 (0.43) | MAPTLMNAHTTKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4761425-A | ANTIASTHMATICS; ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | MERCK FROSST CANADA, INC. (CA) | 1988-08-02 | — | — | US | disclosed |
| EP-0147217-A2 | Leukotriene antagonists | MERCK FROSST CANADA INC. (CA) | 1985-07-03 | — | — | EP | disclosed |